1.   What is JUVÉDERM™ VOLUMA™?

JUVÉDERM™ VOLUMA™ is the JUVÉDERM™ specialty product for volumizing. It is designed for injection in the deep dermis to treat age-related facial volume loss. VOLUMA™ has the optimal thickness of a volumizer while still retaining the smooth nature of the JUVÉDERM™ family.

2.    How is JUVÉDERM™ VOLUMA™ different from the rest of the family?

JUVÉDERM™ VOLUMA™ differs from the JUVÉDERM™ family in that it is a markedly thick, robust product ideal for injection in the deep dermis to treat age-related facial loss. VOLUMA™ achieves this viscosity through modifying the HYLACROSS™ technology and using low molecular weight HA, which enables more effective cross-linking. This produces an extremely highly viscous product with optimal lift capacity that is still smooth and cohesive.

3.    Where is JUVÉDERM™ VOLUMA™ intended to be used?

JUVÉDERM™ VOLUMA™ is indicated for volumizing of the cheeks, cheekbones, and chin. It is intended for deep dermis injection.

4.    Can JUVÉDERM™ VOLUMA™ be injected into the lips?

No. Because it is such a thick, viscous product, JUVÉDERM™ VOLUMA™ is not appropriate for injection into the lips. Other products in the JUVÉDERM™ family (such as Ultra™ or Ultra Plus™) are optimally suited for treatment of the lips.

5.    Can JUVÉDERM™ VOLUMA™ be injected superficially?

No. The robust nature of a volumizer means it must be injected into the deep dermis, otherwise the product may be felt or seen (as discoloration in the skin) or result in an adverse event.

6.    Is JUVÉDERM™ VOLUMA™ injected the same as other JUVÉDERM™ products?

The robust viscosity that makes VOLUMA™ such an ideal volumizer also means that it requires specialized training in order to achieve successful outcomes. VOLUMA™ can be injected through either a needle or a cannula; both are supplied with the product. Regardless of physician choice (needle or cannula), careful training and experience are recommended to become familiar with injecting VOLUMA™.

7.    Is JUVÉDERM™ VOLUMA™ supplied the same as other JUVÉDERM™ products?

Because it is a volumizer, VOLUMA™ is packaged differently than the rest of the JUVÉDERM™. Because volumizing requires greater amount of product, VOLUMA™ is supplied in a 2 mL syringe, rather than a 0.8. VOLUMA™ also comes with both a needle and a cannula, so the injecting physician can choose which to use.

8.    How long does JUVÉDERM™ VOLUMA™ last?

Clinical trials show the volumizing results of VOLUMA™ to last up to 18 months.

9.    What are the adverse reactions with JUVÉDERM™ VOLUMA™?

The types of adverse events VOLUMA™ demonstrates are consistent with other volumizers, but in very low rates. In clinical trials, only 8% of patients experienced an AE such as swelling or hematoma. Additionally, there were no cases reported of product migration, as is common with some other volumizers.

10.    Has JUVÉDERM™ VOLUMA™ been tested in clinical trials?

Several trials have been undertaken with VOLUMA™; both prospective and retrospective. VOLUMA™ demonstrated significant improvement in facial volume loss, garnering high ratings from both physicians and patients. There has also been investigation into VOLUMA™ with HIV patients undergoing HAART therapy (which results in facial lipotropy), with positive results.

11.    Who is the appropriate patient for VOLUMA™?

Patient selection is very important with VOLUMA™, as it is a specialty volumizing product. Patients who can benefit from VOLUMA™ are patients with age-related facial volume loss, which may have resulted in a sunken look or facial asymmetry, or patients with facial ptosis.

One thing to note is that patients with sagging skin are not good candidates for VOLUMA™—these patients may be better served by surgery.

12.    Why should I use VOLUMA™ for volumizing as opposed to another JUVÉDERM™ product?

Although other JUVÉDERM™ products such as Ultra Plus™ or Forma™ do offer robust lift capacity in areas such as the NLF, VOLUMA™ is specially designed for true volumizing, ie deep dermis injections of a thick, viscous product to volumize cheeks, cheekbones, and chin. When restoring or creating volume in these areas, VOLUMA ™ is the ideal product of the JUVÉDERM™ family, because it is our most viscous product that retains the smooth cohesivity of JUVÉDERM™.